Seventy two guinea pigs were divided into 3 groups; 24 each of control, unilateral thyro-parathyroidectomized and bilateral thyro-parathyroidectomiged groups. After the intraperifoneal in jection of 16μCi of radioactive calcium (^(45)Ca) ^(45)Ca uptake of various organs and tissues were measured at the 8th, 16th, 24th and 36th hours, respectively, 18 animals were slaughtered (6 from each group) each time.
The results obtained were as follows:
1. It was shown that each organ and tissue of treated animals had higher ^(45)Ca uptake than the control group, and the bilateralectomized group, higher than the unilateralectomized group, generally.
However, there were some exceptions of the findings. The unilateralectomiged group had higher ^(45)Ca uptake than the bilateralectomized group in case of adrenal gland and femur at the 8th hour, adrenal gland and blood at the 16th hour; spleen, pancreas, adrenal gland, femur and skeletal muscle at the 24th hour; and pancreas, femur and skeletal muscle at the 36th hour, respectively.
2. ^(45)Ca uptakes of each organ and tissue were also determind with respect to time. The results were varied with each treatment group, but generally the highest uptake was shown at the 8th hour and decreased gradually thereafter. The differences were not, however, statistically significant.
3. Femur had shown the highest ^(45)Ca uptake and the next were blood, Pancreas, liver, skeletal muscle and spleen respectively, and the least were adrenal gland and liver, even though there were some variations in the results.
4. The differences in ^(45)Ca uptake of each organ and tissue for the treatment group were statstically significant as compared with the test of the control group, except the spleen and blood at the 8th hour; liver at the 16th hour; adrenal gland, spleen, pancreas at the 24th hour; and spleen at the 36th hour.
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